导师类别：硕导
邮箱：wangqianwq1219@163.com
个人简介
王倩，硕导，深圳大学附属华南医院特聘研究员，2018年毕业于中山大学，获理学博士学位；2020年在中国科学院广州生物医院与健康研究院从事博士后研究；2022年在香港中文大学（深圳）做访问学者；现已在Nature Cell Biology、Cell Discovery、Journal of Biological Chemistry、Journal of Natural Products、Journal of Virology等SCI期刊上发表学术论文10余篇；主持国家自然科学基金青年项目（C类）1项，广东省自然科学基金面上项目1项。
主要研究方向
生物多组学大数据融合和分析、生物分子相互作用模拟和预测
代表性成果等
1、科研论文：
1) Lv, G.Q. #; Wang, Q. #; Lin, L. #; Ye, Q. #; Li, X.; Zhou, Q.; Kong, X.Z.; Deng, H.X.; You, F.P.; Chen, H.B.; Wu, S.*; Yuan, L.*; mTORC2-driven chromatin cGAS mediates chemoresistance through epigenetic reprogramming in colorectal cancer. Nature Cell Biology, 2024，26(9):1585-1596.
2) Wang, Q.#; Zhu, N. N.#; Hu, J. Y.; Wang, Y.; Xu, J.; Gu, Q.; Paul M. Lieberman; Yuan, Y.* The mTOR inhibitor manassantin B reveals a crucial role of mTORC2 signaling in Epstein-Barr virus reactivation. J Biol Chem, 2020, 295(21): 7431-7441.
3) Zhu, N. N.; Wang, Q.; Wu, Z. D.; Wang, Y.; Zeng, M. S.*; Yuan, Y.* EBV LMP1-activated mTORC1 and mTORC2 Coordinately Promote Nasopharyngeal Cancer Stem Cell Properties. J Virol, 2022. 96(5): e0194121.
4) Lin, Y. S.#; Wang, Q.#; Gu, Q.; Zhang, H. A.; Jiang, C.; Hu, J. Y.; Wang, Y.; Yuan, Y.*; Xu, J.* Semisynthesis of (−)-Rutamarin Derivatives and Their Inhibitory Activity on Epstein–Barr Virus Lytic Replication. J. Nat. Prod., 2017, 80 (1), pp 53-60.
5) Wu, T. Z.#; Wang, Q.#; Jiang, C.; Liu, S. N.; Morris-Natschke; Cui, H.; Wang, Y.; Xu, J.; Kuo-HSiung Lee*; Gu, Q.* neo-Clerodane Diterpenoids from Scutellaria barbata with Activity against Epstein–Barr Virus Lytic Replication. J. Nat. Prod., 2015, 78 (3), pp 500-509.
6) Li, H.; Zhong, C. R.; Wang, Q.; Chen, W. K.; Yuan, Y. Curcumin is an APE1 redox inhibitor and exhibits an antiviral activity against KSHV replication and pathogenesis. Antiviral Res. 2019, 167: 98-103.
7) Liu, S.N. #; Hu, J.Y. #; Tan, S.H.; Wang, Q.; Xu, J.; Wang, Y.; Yuan, Y.; Gu, Q.; ent-Rosane diterpenoids from Euphorbia milii showing an Epstein-Barr virus lytic replication assay. RSC Advances. 2017, 7, pp:46938-46947.
8) Pan, X. #; Ye, F. #; Ning, P.R. #; Zhang, Z.Y. #; Li, X.Y.; Zhang, B.H.; Wang, Q.; Chen, G.; Gao, W.; Qiu, C.; Wu, Z.S.; Li, J.C.; Zhu, L.Z.; Xia, J.; Gong, K.Z.; Du,Y.; Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2. Cell Discovery. 2023, 9:118.
9) Wu, Z.S.; Chen, G.; Qiu, C.;Yan, X.Y.; Xu, L.Z.; Jiang, S.R.; Xu, J.; Han, R.Y.; Shi, T.Y.; Liu, Y.M.; Gao, W.;Wang, Q.; Li, J.C.; Ye, F.; Pan, X.; Zhang, Z.Y.; Ning, P.R.; Zhang, B.H.; Chen, J.; Du, Y.; Structural basis for the ligand recognition and G protein subtype selectivity of kisspeptin receptor. Science Advances. 2024, 10, eadn7771.
2、近五年主持或参与的项目：
1)国家自然科学基金，青年基金项目（C类），2026-01至2028-12，主持；
2)广东省自然科学基金, 面上项目, 2025-01 至 2027-12, 主持；
3）国家自然科学基金, 面上项目，2025-01-01 至 2028-12-31, 参与。
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